GPU, not CPU, to be specific. I don't have any problems with my AMD CPU, but I've seen firsthand it goes quite slow on Intel graphics (although occasionally one is seen that works fine -- go figure). When they say they only support NVidia/ATI, they mean it..
(I have no problems with my 5 year old workstation with Quadro FX, nor my current desktop with GTX550Ti. Curiously, Altium 15 runs in XP on the workstation, and used to work on the desktop, but something about buggy DirectX, I think, prevented it until finally migrating to Win7. Works as well or better now.)
Also, works great with an SSD, not nearly as intensive for HD access as something like SolidWorks, but completely removes the bothersome delay during autosaves or what have you. (I've worked out of online (VPN, cross-country connection) network folders before. Oh man, the saving sucks. But hey, if you're just doing a touch-up..)
Tim