You would connect one of the GPIOs to MUX_A or MUX_B. Two GPIOs if you want to control three or four devices. See the 74HC4052 datasheet for how the A and B pins relate to the 0/1/2/3 outputs. Whichever pin you do not connect to your micro will be pulled low by the 1 kOhm resistor, so connecting one of the inputs if sufficient if you only need to switch between two outputs.