I second what the guy above me said, but with one caveat.
The fuse bits for each AVR chip are very different from each other, and it's easy to brick them. If you make a mistake, you can eliminate your ability to ISP program them. You can always use "high voltage" programming to get them back. What that really means is applying 12 volts instead of 5 to the RESET pin.
Or you could just throw it away. They're, what?, a dollar-fifty or so each maybe?
This may, in particular, be my particular orientation because I use SMD chips, and in general you wouldn't be able to engage the HV programming mode with the device in-circuit. Replacing it with a new one is very much the path of least resistance, and then to recover the removed one, you'd need a ZIF SMD socket for your HV programmer, and the whole exercise for me becomes just... meh.