So you're saying that building one yourself will give better results than the modules? Allow me to doubt that.
Yes. You dont need to doubt it, it is how it is.
It is really easy to understand, if you think about it.
The isolated converters are just a PWM signal fed into a transformer. The transformer is driven to saturation (EMI everywhere). There is absolutely no regulation. Meaning that if you do something on the output, draw current, your voltage will go down. And if your input voltage is only 4.5V for a 5V model, then your output is 10% lower. If your input has a 1KHz ripple, it goes to the output.
Meanwhile if you take a boost-invert topology, there is immediately feedback if the output changes. The inductors are driven with just enough current and it is nice and silent.
Also, you have 100mV noise where your signal is about 1 Volt. In frequency ranges where the opamp doesnt have any PSRR.
Yes, you can filter it, but it is not smaller task than designing a proper (and not isolated) DC-DC.
A homespun DC-DC doesnt have to be coming from the junk bin. I personally can solder QFN package with a chinese hot air station.