When you get your nose truly stuck into the finer points of layout you end up focusing more heavily on the signal return path than the actual signal (or atleast equal consideration)
As you use higher frequency signals a larger portion the return current will want to flow along the path of least impedance vs the path of least resistance, even with picosecond edge speeds there is still a small fraction of the current that wants to travel along the path of least resistance (not much but it exists),
this is why for digital and RF people focus on a nice big ground planes for the path of least impedance, to clarify by path of least impedance i mean that the signal will want to return as close to the path of the original signal as possible, and the better this path is followed the lower the effective impedance of the signal trace,
Any deviation from this route say a break in the ground plane and the return current has to veer off, go around the deviation and return back to the path it was following, this causes an impedance mis-match in the signal which can cause things like reflections and radiated emissions, (think stub antenna's) and breaks into ground loops a little, with decoupling caps being a golden example of this, with most people placing the positive pin close to the cap and leaving the ground plane to deal with the negative connection, when in reality the current will be trying to trace along the current path through your IC.
At the low end living mainly with path of least resistance you tend to find people running dedicated earth traces or star grounds to keep things at the same potential (generally analog) as all traces have resistance and as such all ground traces create a small voltage deviation from the supply ground, equally you may find analog segments isolated on there own little ground plane island, this is generally to keep larger currents that would cause a greater voltage deviation from crossing it,
breaking the ground planes can introduce radiated noise issues if there are any fast edges about, and just because your op amp is controlling something slow will not mean that its output can not move quickly due to a high gain, but this is diverging into slew rate limiting..
Now with most of this stuff there is no exact right and wrong, to throw a spanner in the works of most books, have a think about a high speed analog system, you will want to maintain a path of least impedance, but also keep large currents away from your circuit, which becomes more difficult as floating it on its own little ground plane and having any form of break or deviation in the path of least impedance makes a lovely little RF noise source, this is why on some designs you see little capacitors stitching ground planes together, it provides a lower impedance path for fast signals than otherwise, reducing the voltage developed over the gap and reducing the amplitude of the emitted RFI