I use tons of the paper board stuff, it's good for quick easy prototyping, a normal solderless breadboard is still useful for quick prototyping too depending on what you are doing, if I am going to do a bit more complex of a board I will usually send it off to ITEAD. If you are doing something like say a radio, I would recommend more to use basic copper clad as a ground plane like previous suggested, really it all matters what you are doing, making a simple AVR circuit? You will pretty much be OK doing it on a breadboard, making a switching regulator, paper board will work well, making am AM radio, use copper clad, want to make a nice clean, tight board with SMD, go with something like ITEAD. I keep a bit of all methods available.