I've never used Multisim, but I assume it follows common convention:
"U" is a component prefix for ICs in a schematic. (Like how R is the prefix for resistors, L for inductors, Q for transistors, etc. e.g. R3, L23, Q2.) So U1 means "IC 1".
The A/B suffix means the specific functional block within a chip that has more than one. The LM358 is a dual op-amp. So U1A means the first op-amp, and U1B means the second op-amp, within the same chip.
None of this is specific to the LM358, which is why it's not on the datasheet.