I used one of this in 1989/1990 to do my final year EE Project.
It involved comparing a Spice model of a transistor against a real junction on a silicon wafer.
The HP85 was connected via GPIB to a Parametric Analyser which was then connected to a wafer probe station with a single wafer on it.
I recall it was all done in BASIC but was quite powerful.
I got a Distinction for it so all was good !