I find it hard to believe that even ham-fisted soldering would damage the PCB so locally, so my guess is a severe overload. I can not immediately see from the schematic where the OHMA node is connected to, but looks like it senses the high voltage and adjusts the current source if that is out of range. So maybe a severe overload on the sense connections could do this? I know there are a bunch of series resistors, but the sense terminals are only rated up to 350 V and I do not think they are protected by spark gaps of MOVs, so maybe feeding them 1000 VDC could do this?
After that somebody tried to desolder the part and ripped off all those pads.
Looks like a nice project for TiN if he is bored
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It is funny that all self tests pass. Guess they do not test that part of the current source, and means that repair might be feasible assuming you are skilled at repairing pads. But obviously in a severe overload a bunch of other components could be damaged. Though nothing else in the picture is obviously damaged.