Dave,
Two topics I would be interested in are:
1) The changing role of the VC. With funding sources like Kickstarter, IndieGoGo etc., why should a start-up deal with a VC (and give up a lot of equity)? Also how has the role of the VC changed in the last few years and what do they have to offer beyond money? Related to this is that it often costs much less to bring a kickstarter project to market then it cost to setup a lab, build a prototype, bring to market etc 10-20 years ago.
2) Is education doing a good job of preparing people for an entrepreneurial world? Traditionally someone getting a EE (or most other) degrees would set his sights on getting a job as the first step in life after graduating. It was not that long ago that a lucky (and good) engineer could look forward to a decades long career with a major firm like IBM or Bell Labs. Today senior engineers in their later years (50 +) often face layoffs and seem for whatever reason to have difficulty becoming an entrepreneur. My theory is that the problem does not lie in the mechanics of doing a kickstarter project for example but rather the belief system that most workers have internalized over the years which make them prisoners of their own minds. On the other end of the age spectrum, here in the USA at least, there seem to be lots of college graduates in their early to mid twenties who are either unemployed or under-employed; why don't we see more of these people being entrepreneurial, even if it is a side business while they work a day job at McDonald's?