Those strings you have to send to the R6581 to read data.
I try with Excel but it is slow
Range 10V DC and one NPLC
instrument.WriteString "*RST"
instrument.WriteString "CONF:VOLT:DC"
instrument.WriteString "VOLT:DC:RANG 10;NPLC 1"
instrument.WriteString "ARM:SOUR IMM"
instrument.WriteString "ARM:LAY2:SOUR IMM"
instrument.WriteString "TRIG:SOUR IMM"
instrument.WriteString "INIT:CONT OFF"
instrument.WriteString "ABORT"
instrument.WriteString "READ?"