What exactly is your set up? And what does automotive have to do with it? You mention it disconnects from your laptop... is this inside your car? whilst looking at your car? or whilst being 'powered' by the vehicle ?
I'm assuming - from the fact things 'reset' whenever you 'crank' - that you have something powered from the cars electrical system, in which case you will have to deal with large transients, sudden dips well below 12V, and general hellishness. Its a less-than-ideal power supply, so would require heavy filtering, protection, and decent capacitance after a diode to take up the slack.
I could be wrong, but your post just reads like you have an issue with USB... that is somehow linked to your car...