I've switched to using the MCP2221 for just about everything. It works without drivers in any modern OS (Win 8+,Linux, OSX), and has a bunch of nice-to-haves as well (ADC, I2C, GPIOs).
What MCP isn't telling you though is that the MCP2221 is actually just a PIC with factory loaded firmware and different labels.
Not that it matters in the end, but it's a fun fact.
I do however have two minor issues with the MCP2221.
The first one is that it won't go faster than 115200bps, and I have exactly _one_ device that insists on running 921600bps (yep, almost a megabit over serial).
The second one is that it won't go lower than 3.0V, so if you're interfacing with 1.8V stuff, you'll need to level-shift.