So are people sharing an OS virtual disk between their various VMs?
With WXP I could get the OS, a toolset, and a set of projects, on a 10G virtual disk, and that wasn't so bad. But W8 is much larger (30G according to "system requirements") and does seem as tunable for smaller systems, and that starts to get painful. Sharing a single W8 OS disk and putting the tools and projects on separate disks would be OK, except that most tools tend to heavily pollute the OS disk with DLLs and such. Sigh.
My experience (Older Mac Pro 8core/10Gmem host, Virtual Box, no SSDs) has been pretty pleasant. Host OS disk caching seems pretty effective; the first time you start up AS6 (for example) is pretty painful (as it is on real hardware!), but subsequent startups are better, even if you've rebooted the VM in between.
Don't start up enough VMs that your host starts swapping/paging, though! Ouch! (2G has been enough RAM for WXP VMs.)