The O2 is great for most headphone loads. Drives everything I have more than loud enough and distortion free. Even at high gain there is no hiss.
I've built some Cmoys, and they don't really compare to the O2, but they are cheaper.
Output power is a bit limited though, especially with TLE2426 versions. I was working on a circuit to fix that and to get better battery life while still fitting in the traditional Altoids tin, but never got it done...
Just beware the maximum input level on the O2 as it can clip there. For most purposes it isn't a problem, and certainly not as big as others have made it out to be.