Probably not, as the gate charge has to go somewhere whenever it switches and will cause current injection, mostly to the source, but some to the drain. Also the body diode means that unless you use two back-to-back (in series, source to source), with a pulldown on the source to pass the gate return current, you'll have problems switching AC signals.
Look at Photo-MOSFET optocouplers. The control circuit is fully isolated, they don't inject charge, and typically already have a back-to-back MOSFET pair internally with no need for a pulldown.