I actually like teflon wire alot, for chassis wiring its really great and its hard to find another reason to use other wire inside of the chassis in most cases, as stiff as it is.
I did have the feeling that if you have a heavy in soldered cable harness, or somethin you can't disconnect for some reason, and you need to unscrew and move a subassembly, the teflon insulation was putting a bit too much stress on the solder joints when it was moved around though...
Maybe my final thought on the matter is: teflon is great when you finish a prototype that you think will have excellent field reliability and you are ready to go into manufacturing. The extra expense is probobly not work it in a prototyping environment where you might need to adjust stuff alot and have bootleg mechanical design.
I kind of get this feeling when I use PVC insulation that I am being a cheap fuck, with the other problem silicone insulated wire also seems to not work great with conventional wire cutters. I also need to weaken and tear it, other wise I had a decent probability of getting nicked conductors.. but it was OK with a 10$ klein tool one so long you were careful.. but it was not a go/no go operation, definatly working in the 'analog zone' of the hand tool.
But silicone wire is too nimble to be used inside of a chassis in most cases, unless you figure out the wire harness and put all the zip ties, heat shrink and jackets its gonna look like someone poured a buncha pasta into your chassis. I do like it for custom cables, but I am not really comfortable using it for things other then careful lab work unless it has nylon or other jacket material on it.
Because of this I only ever invested in cheap klein-tools wire strippers. I need to find a good teflon wire solution. I think what I did when I worked with teflon wire alot (now I honestly kind of forgot), was use light pressure and rotation to weaken it, then use the larger hole to rip it after its weakened.. it kinda worked... but the standard for the teflon wire was to use a bench pnumatic unit with micrometer adjust. That kind of tool is just way too expensive for my home use unfortunately.
I kind of want a kit of 1 foot long lengths of all the different insulation materials to play around with in a few different gauges. I need to ask for a wire sample kit. Then maybe a sane choice about high end hand tool strippers can be made
I think someone once recommended that one of those adjustable 'flat' wire strippers should be used for kynar. They are like 30 dollars and have the appearance of a razor-blade floor scraper. It does not seem like the right tool for heavy use though.