Believe it or not, we actually just released a video today where we discussed this:
Just a warning, it's not the most thrilling series but covers a lot of topics.
Essentially, this class of scope has one acquisition system per two channels. So, you can spend 100% of your ADC on one of those channels (5 GSa/s) or split it between two channels (2.5 GSa/s). If you have a four channel scope, you basically have two acquisition systems and can get two channels running at 5 GSa/s. Usually this means you can use 1 OR 2 and 3 OR 4 at 5 GSa/s. I believe some manufacturers may mix up the channel numbering scheme, but this is pretty industry standard. An easy way to check is to turn on one channel (at 5 GSa/s), and see if you can turn on one of the other channels without halving your sample rate.