One net seems a rather trivial case, just hand route it. Or if not doing the layout personally, add a note to do such.
In general, to get the autorouter to use different sizes on a given net, either:
- Use a net bridge to split the net
- Use, well they used to be called From-Tos but there's a new system now, anyway, routes can be controlled by region, associated components, topology, etc. I think.
Tim