I've run AD9 through AD16 on a 2008 Mac Pro and 2009 & 2012 Macbook Pros, over a range of OS X versions, under Parallels-hosted Windows 7 VM's. No serious issues. 3D works smoothly. 3D mouse works fine.
I had Office 2008 installed on the Macs, and did not bother to install a windows version of Excel on the VMs. Parallels allowed AD to invoke the Mac-installed Excel to generate BOMs from templates. When I updated my Mac Office version to 2016, that feature stopped working on the Mac Pro, and I had to install Office 2007 on the VM to be able to generate BOMs again. Kept Office 2008 on the Macbook, and still works fine with AD16, via Parallels.