You need to figure the Thevenin equivalent of the resistors. So, that would give 144Hz, not 72Hz.
That's still ~3200 samples, a huge amount for such a simple micro to be working on. If it can take its time (or say a few seconds), that's fine at least -- enough time to do most analyses you'd want to do. Uh, give or take how much time is spent diddling with external memory, anyway -- the linked device only has 2k SRAM, which will hold at most 1k samples of unpacked 12 bit audio, so you'll need external to hold onto that much at once. And if it's slow like SPI RAM, it'll take quite a few cycles to get at; at least DMA can handle that in the background.
Being able to doing a synchronized acquisition, and comparing to a reference envelope, is promising. You'll have to build a statistically representative sample set to derive go/no-go values from, and analysis on that will also tell you whether the method is effective, or if more detailed analysis is necessary. Remember, that 3200 sample buffer is a 3200-dimensional vector: I'm not kidding when I say complexity is exponential in length! There is a lot of volume inside a 3200-dimensional cube. If your analysis is reliable/effective enough using only simple linear and statistical methods, that greatly reduces the complexity of that space (down to perhaps linear or quadratic with length, or even less than that, as there's really only so many linear algebraic operations you'd want to perform on a single vector). For example, vector norm (= RMS) and FFT (= multiplication by DFT matrix) are common signal processing operations that might be used. Subtraction against a reference works, if every single dimension of both vectors cancels out very neatly -- but with 3200 dimensions, what are the chances of that? Maybe doing statistics on the residual would prove valuable.
If this is like, mass production test equipment, it will be well worth doing all this analysis, gathering reference data and preparing a method; if for just a few off, like... would you not be better off just reading the output with a scope and eyeballing it? Economy matters too!
Tim