Such auto layout tool hasn't been made and probably won't be in the near future. The problem is way too complex.
Some dedicated layout generators do exist, for example the TI Webench which basically crunches and modifies TI's pre-built power converter layouts to suit the user parameters. IMHO, they are of little value.
What comes to your question, depends on circuit. Sometimes it just happens that a certain circuit schematic works very well on a breadboard, and if this is the case, the optimal PCB layout would look similar.
But, a PCB design gives you so much more freedom, especially if you can afford extra layers. Given a fixed circuit complexity, the more you have layers to work with, the easier everything gets.
Trace angles are electrically irrelevant unless we are talking about really high-speed radio frequency stuff.
On the other hand, good reference planes (contiguous ground pours, preferably at least one layer dedicated to ground only) tend to be very important in many different types of circuits (almost anything but the simplest very low-frequency stuff): power converters, seemingly low frequency stuff that still have high edge rates (think about a 8MHz microcontroller), sensitive analog stuff, high-speed digital circuits, or, of course, RF.
But a circuit consisting of a connector, series resistor, and an LED wouldn't care about a ground plane.