Search from Internet for reference, But not sure there are OSX versions.
1)Protel more used in china, protel 99se, protel DXP, Altium, these are a company's constantly upgrade software;
2) Cadence spb software is Cadence software. ORCAD schematic design which is the international standard; The PCB design, simulation, very well equipped.
complex than protel.
3)Mentor's BORDSTATIONG and EE, which BOARDSTATION due only applies to UNIX systems not designed for the PC, so rarely used.
4) EAGLE Layout ,this design software is most widely used in Europe .