I think the main problem with using polystyrene is we have not made those parts in decades.
100pF caps measured with BK @ 10kHz, CD-ceramic disc PS-polystyrene
Type, val, ESR, Q
Mica, 100.5, 200, 1300
CD, 97.5, 1640, 100
PS, 102.8, 77, 2200
Air 98.9, Q hunts, Dissipation factor 0
500pF (PS 480pF) measured with BK @ 10kHz
Mica, 520.1, 23, 1300
CD, 481.2, 540, 64,2
PS, 481.6, 10.5, 3500
Air 486, Q hunts, Dissipation factor 0
***
Uncalibrated, looking at S11 impedance of the 100pF PS vs air capacitors