If it's got a center pad, it's likely not glued. A hint that parts are glued is to look for nearby passives, if you can see the (usually red) glue underneath, then the other parts may be glued as well.
Most likely you're not applying enough heat to the part. The EPAD will be soldered to the ground plane, which is drawing heat away from the IC. Just keep at it for a while, maybe at a slightly lower temperature than 400 C. When the board is nicely heated up, ramp up the temperature and focus the hot air on the IC alone.