Assuming you are talking about the stuff around the edges of the schematic sheets, it generally bears no relationship to locations on the PCB.
Where it is useful is that it makes it possible to have automated test gear print something like "U47, Page 4, location C3 is not responding", which is helpful when trying to repair some bit of industrial kit.
Old HP test gear was sometimes spectacular for this:
"PLL Lock failed : 60% A11 Reference board, 25% A10 DIF Counter, 10% Power supplies."
And they had this sort of thing for all the self tests, expensive and time consuming to create, but utterly wonderful.
Regards, Dan.