Unless you are doing some kind of specialist connector with a specific type of compression crimp or something, there are plenty of cheap or affordable tools to do the job. The Japanese Engineer crimpers can do pretty much any kind of open barrel "wing" type connectors. You have to do the wire crimp and the insulation crimp separately but this is what makes the tool so flexible. For small volumes of crimping that most people here would do, they are more than adequate at doing a professional job. You just need to take a bit more time doing them than the expensive product specific crimpers.
If you are doing thousands of Molex crimps, then the proper tool is worth having, as it does both the wire and insulation crimp with perfect results every time.
I've used my PA-09's to do plenty of JST connectors as well as Molex ones (KK series to be exact). When you start going to the larger automotive style plugs with bigger pins, you'll run into issues. I tried doing a 35pin AMPseal connector with my PA-21s, and the pins were just too big. The crimp around the insulation wasn't perfectly round and it lead to issues getting the wired up pins to sit correctly in the housing. Still worked out ok, and we didn't have the budget for the proper tool just to do 4 connectors.
There's a large list of what they do work with from JST, Molex, AMP etc here:
http://www.engineer.jp/en/products/pa09_20applicatn_chart.htmlThings like wire end ferrules are applicable to just about any tool that works. As are insulated terminals or open barrel terminals. You can get cheap ratcheting tools for under $20 that do the job well. If you're into RC hobby stuff, JST red connectors are great for inline power connections. Dupont pins and housings for projects make things much neater.
My point really is to show that with a little investment in some rather cheap tools, you can get much nicer professional results without that stigma of thinking you need a $400 tool to do so.