The packages you want to consider, in arbitrary order, are Eagle (very popular, mature, UI takes time to learn), Dip Trace (supposed to have good UI), Kicad (open source, getting promising, not mature) and Circuit Maker (limitations on keeping your design private or saving them on your computer). Just play with them and see which one you like.
For PCB manufacturing process check pcbshopper.com
I am using Eagle, may switch down the road to Kicad.