Taking NFC literally, no. You can make an asymmetrical field, but you can't make a field stop arbitrarily (no matter how many times the textbooks draw diagrams as if you could). To be exact, the field satisfies Laplace's equation, \$\nabla^2 \phi = 0\$.
A very large antenna (in human terms; a dozen meters or so) can have directional gain (i.e., better than dipole) in a propagating field, but that's not near-field.
The usual approach is to place a coil over a ferrite plate, which acts to short out the magnetic field lines on that side. This reduces the volume of field (reducing the magnetic path length more than the effective area is reduced, hence the inductance goes up), giving less range on the open side, and higher mutual inductance up close.
The shield is as much practical as anything: it improves coupling between coil and target, and shields the circuitry underneath, allowing a compact build.
Tim