Note that IC2 is an inverting amplifier. When operating from a single supply (+5V here), an intermediate voltage (+2.5V here) for “virtual ground” is mandatory, since as its input goes positive the output goes negative (and vice versa). In the old days, split supplies were used with “real ground” so that the output could go positive or negative.
Any op amp will work with a single supply: the question is what range of common-mode input voltage is tolerable and what range of output voltage can happen. Older op amps intended for split supplies often require input voltage (common mode) substantially positive with respect to the negative power terminal. Newer units designed for single supply operation can have input voltage somewhat negative wrt the negative supply, but the output is always positive wrt that terminal (grounded for single supply operation).
To forestall quibbling, there are very few op amps with an actual ground terminal (e.g., uA702) and some special ones have internal charge pumps to enable the output to go a bit negative of the power supply.