When using lots of high current LEDs like this I prefer to use switching power supplies to generate a voltage at or close to the forward voltage drop. That minimizes losses and tends to be more efficient.
Yeah, this is a more expensive approach, but easy to do (especially if you use an off-the-shelf complete switching DC-DC module) and definitely yields a superior end product.
Wouldn't it be cool if the switching reg could look at the excess voltage on the TLC pins, and use that as feedback (instead of its own output)? Then you wouldn't need to carefully tune the switching reg output voltage to the optimal setting; the circuit would be self tuning in that respect. It's tricky though, because measuring that excess voltage would involve an array of diodes at the very least, so whether it's worth the complexity is debatable. Would have been cool if the TLC chip could have done all this internally and provided a feedback signal for regulators.
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