At an SPIE meeting I attended, a Swedish group had produced an impressive high-resolution x-ray detector, using microlithography techniques to fabricate a gas ionization detector with very small cells. They were targeting this device on x-ray mammography, which requires high spatial resolution. With the small cells, it was practicable to operate the device in counting mode, rather than measuring the output current. They pointed out that the statistical noise at low doses was less obtrusive in counting mode than the electronic and dark-current noise in a current-mode detector. To demonstrate the performance, they presented images of fish with very fine bones.
After the presentation, one member of the audience stood and said that was the best example of "Poisson imaging" that he had ever seen.
Half of the audience laughed. My boss, sitting next to me, missed the joke.