I mean, of course not, and this is obvious to us engineers.
What I can't understand is why it is also not obvious to ordinary Joes: there is an entire power grid on the other side of that cord. What difference CAN a single fuse actually make when you have 100km+ of power line, transformers, switch gears and (gasp) non-audiophile fuses in line with your stereo?
Don't forget your house will likely have an incoming fuse - you'll want to make sure that is upgraded too. The MCBs in the consumer unit could do with gold plate treatment on the contacts, just in case. While you're at it, make sure the twin and earth is made of oxygen free copper.
It only takes a few minutes of thinking to realise how minimal this one component actually is in the system and how it can't make any practical difference. But people will still buy these. A fool and money are soon parted.