General > General Technical Chat
Covid 19 virus
SilverSolder:
--- Quote from: Miti on March 29, 2020, 12:08:40 pm ---
Is it possible that it [Covid-19] was here long before we knew it?
--- End quote ---
It seems possible, but a proven good antibody test doesn't actually exist yet as far as I know, so we can't actually answer that question.
The tests that we do have (the ones used by hospitals) only show whether a patient currently has the virus, not whether they have had it in the past (which requires the non-existent antibody test).
coppice:
--- Quote from: Zero999 on March 29, 2020, 01:15:07 pm ---
--- Quote from: bd139 on March 29, 2020, 11:12:59 am ---Chloroquine is nasty shit. Even if it is effective it should be last resort. Can cause permanent cardiac damage. Also on top of that so can Covid-19 apparently. Smells like a damage amplifier.
--- End quote ---
Every treatment carries an associated risk. Even being put on a ventilator carries a significant risk, because it involves being sedated, administered muscle relaxants and lots of tubes being poked into various orifices.
--- End quote ---
Too many people have a poor grasp of the term "recovering from a disease", and treat it like it means everything works out great. The reality is recovering just means you didn't die. The long term effects are frequently quite severe.
Cerebus:
--- Quote from: MasterTech on March 29, 2020, 07:59:18 am ---*About the zinc issue:
Taking zinc is highly recommended, as it has strong antiviral activity. Moreover it is being reported that chloroquine is actually successful because it is an ionophore of zinc, ie it increases its concentration in the cells.
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1001176
--- End quote ---
Please, you don't have to read further than the title to realise that at this stage this is irrelevant:
"Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture"
In Vitro = In Glass = "in a test tube" and In Cell Culture = "in isolated, individual money kidney epithelial cells* in a tissue culture bottle" i.e. in an isolated laboratory setting, not in a whole living organism, let alone in a controlled, double blinded clinical trial.
If one doesn't have the background to put the implicit context around a biochemistry paper so that one understands what it is saying, what it is not saying and what this means (or does not mean) for real world therapeutic applicability then this is not the time to be trying to read papers like this in isolation.
Would you react the same to a paper titled "Cl- Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Blocks the Replication of These Viruses in Cell Culture"? Because I can assure that the science behind that title, made up just now by me, is good. It would work, it would inhibit coronaviruses. In fact we (almost) all know that already, but if you don't know why my imaginary paper holds out no therapeutic possibilities, then you most definitely don't have the beginnings of what it takes to read the actual real paper cited and know how to interpret it in context.
The one thing that paper most emphatically does not say is:
--- Quote from: MasterTech on March 29, 2020, 07:59:18 am ---
Taking zinc is highly recommended, as it has strong antiviral activity.
--- End quote ---
That you, not the paper, have made that recommendation is unsupportable by that paper.
*Vero E6 cell line, as cited in that paper.
Siwastaja:
--- Quote from: blueskull on March 29, 2020, 03:17:11 am ---Sure, and my own mom has asthma. But isn't it more productive to follow health care authorities' recommendations than to waste energy worrying and discussing this all day long?
--- End quote ---
It's easier for you to say, being from a country where the officials have a good idea of what they are doing.
Many of us are from crippled political systems where the proper response comes way too late, and with way more difficulties than it should.
vodka:
Here , some associations are presenting complaints by imprudent homicide versus the management of the COVID by the goverment : First minister: Pedro Sánchez(Falconetti) and Ccaes director Francisco Simón ( Center for Coordination of Health Alerts and Emergencies).
https://translate.google.es/translate?hl=es&sl=es&tl=en&u=https%3A%2F%2Fwww.elconfidencial.com%2Fespana%2F2020-03-26%2Fdenuncia-pedro-sanchez-prevaricacion-maniestacion-8m-supremo_2518964%2F
https://translate.google.es/translate?hl=es&sl=es&tl=en&u=https%3A%2F%2Fwww.madridiario.es%2Fasociacion-consumidores-querella-fernando-simon
Navigation
[0] Message Index
[#] Next page
[*] Previous page
Go to full version