I was affected with serious Carpal Tunnel Syndrome, and 10 years ago I was treated surgically at the right wrist.
Now sometimes I feel some pain in my right arm, but it is sufficient to held the arm in an upright position to stop the pain in less than one minute.
This reduces blood pressure in the carpal tunnel, and the movement was useful even before surgery.
At those times I tested every mouse, trackball and tablet+pen combination I could find, and opted for a Logitech mouse that is out of catalog by almost 10 years: a big, triangular one, made in two versions (one for right and one for left-handed users).
I'm ambidextrous (or better, I was left--handed when I was a child, was writing with the left-hand but had to learn writing again with my right hand at the elementary school: in 1956 that was the rule, here), but I feel very uncomfortable using a mouse with my left hand.
I think Dave should see a doctor: self diagnoses need a professional confirmation better with some instrumental tests.
Best regards