For the actual phase deviation between 2 signals, that's not hard to calculate out, you have your sample rate of 48KHz, so lets take top of average joes hearing, 20KHz,
1 sample time is 0.00002083 seconds,
1 Cycle of 20KHz is 0.00005 seconds
0.00002083 / 0.00005 * 360 = ~150 degrees Phase Shift,
Now lets try down in the middle of human hearing,
1 Cycle of 4KHz is 0.00025 seconds
0.00002083 / 0.00025 * 360 = ~30 degrees Phase Shift
Now personally seeing as our hearing has to normally account for 625 µs of delay from ear to ear, Its not likely to affect your listening experience, but a fixed delay from one ear to another will make your brain derive direction information from the sounds, e.g. you would perceive it arriving from an angle, not straight above your head as inphase audio normally does.
So to put it to the test yourself, you can easily use something like audacity to insert a fixed delay of 1 cycle time between 2 audio channels and see if it sounds any different, At a guess you would hear it from an angle, I know some songs have used this effect for multiple singers so you end up perceiving them to your left and right,