General > General Technical Chat
Vaccine
<< < (38/50) > >>
SeanB:

--- Quote from: nctnico on May 29, 2021, 01:45:51 pm ---That is a good point but the reality is that there is no good choice here. Short term it is clear that vaccinating people saves more lifes compared not doing so. Long term we don't know it yet. A number of people (starting from 20 years old!) who recover from Covid-19 appear to have long lasting effects from it and will require medical care and/or will be mildly disabled for the rest of their lives. We'll have to see how that balances against the long term effects from the vaccinations.

--- End quote ---

True, if you have existing immune issues you get long Covid, know somebody like that, lucky for her she survived as well, but still is suffering after effects. Unlike her family, where there now is a new row of plaques on the wall. Hits old, hits young, kills one in 20 or so, and disables 1 in 200 or so. I probably have had it as well, because the flu last year was something that put me down for 2 weeks, not at all usual. Test  by nasal swabs though has up to 30% error rate either way, unless you do the antibody tests.
G7PSK:
I really don't understand why people are so against the idea of mandated Covid vaccination especialy for foreign travel after all for many countries it is already obligatory for things like yellow fever, Hepatitis and typhoid. I know people who willingly take these shots to go on holiday and carry the car but don't want  covid on the same list even though they already have had the shot.
madires:
A team at Uni Frankfurt investigating blood clots caused by COVID-19 viral vector vaccines thinks it found the mechanism behind the rare side effect. They say that it should be possible to modify the viral vector vaccines to avoid triggering the blood clots.
Link: https://www.euronews.com/2021/05/27/why-are-aztrazeneca-and-j-j-vaccines-causing-blood-clots-scientists-claim-they-have-the-an
DrG:
As soon as I became eligible, I spent an hour or more a day searching for an appointment. Within a few weeks, I received the first dose and three weeks later, the second dose of an mRNA vaccine. Undesirable effects were minimal after the first dose (site pain) and after the second dose about 18-24 h of general fatigue and some myalgia. Basically, I didn’t do much during that time other than lying around, but it was no big deal and resolved completely.

Approval of any vaccine is country dependent but is always an evaluation of the benefits versus the risks and potential risks.

In the US:

Emergency Use Authorization (EUA) is only granted when there is a declared state of emergency and no other approved treatment of that kind exists. In this case, it means no other approved vaccine; it does not mean different kinds of treatments.

With an EUA, the manufacturers cannot control distribution as they can with a fully approved product. If the state of emergency ends, they can’t market the product at all without having full approval (some kind of compassionate use possibility exists, at least theoretically).

In general, the difference between EUA and full approval (FA) is the number of people studied and the length of time they are studied. Again, in general, this means the Phase III and beyond trials as well as post-approval use.

A big part of the EUA is open and public discussion of the data collected thus far (and the data that has not yet been collected) with many independent (non-Government and non-company) physicians and scientists. I watched more than 24 hours of such approval meetings and discussions and much more was available.

Evaluation consists of the product itself, any additional compounds, particularly adjuvants and all of the manufacturing processes involved.

I believe Pfizer has applied for FA (or is in the process of doing so).  I would expect others to follow if they have not already done so.

Along with FA is the labeling which includes restrictions and contraindications.

https://www.fda.gov/vaccines-blood-biologics/vaccines/emergency-use-authorization-vaccines-explained
https://vaccine.unchealthcare.org/science/vaccine-approval/whats-the-difference-between-fda-emergency-use-authorization-and-fda-approval/
https://www.adventhealth.com/blog/coronavirus-vaccine-eua-vs-fda-approval
https://www.verywellhealth.com/pfizer-and-biontech-seeks-fda-full-approval-5186423

JohnnyMalaria:

--- Quote from: coppice on May 29, 2021, 12:11:52 pm ---
--- Quote from: Zero999 on May 29, 2021, 12:01:07 pm ---I stopped listening at the point he starting talking about profit and the amount of vaccines children get, which are both irreverent to the UK. Children don't get that many vaccines here and the most commonly used COVID-19 vaccine, made by AstraZeneca hasn't made them any money. In fact they've lost money on its COVID vaccine.
https://www.wsj.com/articles/astrazeneca-lost-money-on-its-covid-19-vaccine-11619771934

--- End quote ---
Astra-Zeneca fully intended to make a killing with their vaccine. They have simply failed in their political moves, and not sold as much as they hoped they would.

--- End quote ---

AZ are required to sell with no profit during the pandemic period. They would have made no money even if they hadn't monumentally screwed up.
Navigation
Message Index
Next page
Previous page
There was an error while thanking
Thanking...

Go to full version
Powered by SMFPacks Advanced Attachments Uploader Mod