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Vaccine
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NiHaoMike:

--- Quote from: Zero999 on March 16, 2021, 06:47:46 pm ---I do agree we need to cut our use of antibiotics and develop new ones. It's possible the next pandemic could be caused by an antibiotic resistant bacterium.

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--- Quote from: madires on March 16, 2021, 03:07:07 pm ---Antibiotics are meant to deal with bacteria, not viruses. But it's true that we use way too much antibiotics, not just in human and veterinary medicine but also in industrial livestock farming which is possibly the larger threat.

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Indeed, they should rapidly phase out factory farming. I hope that if factory farming causes another pandemic, it would be one that decimates factory farms but cause little or no harm to humans or sustainably raised animals.

--- Quote from: Nominal Animal on March 17, 2021, 01:53:18 pm ---Particularly funny/weird/sad is that the most effective way to stop the spread of pandemics is to restrict human movement, drastically: no exceptions, even for the super rich or politicians.

So simple, yet so costly and difficult.  Proven to save lives, but how do you calculate potential losses, or how much is a single avoidable death worth?  How do you balance the near-term loss of life with the long-term loss of life due to increased statistical financial hardships?  It is not easy.

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Hence why I'm strongly against reopening schools early, since school has become bloated and overpriced. In its place, we could have online learning services instead. Hands on activities (e.g. science experiments) could be done by sending kits to the students or small workshops could be opened if that's not practical, done in such a way that possible spread would be very limited.
Circlotron:
I wonder what would happen if you got the first dose of one brand of vaccine and the second does of a different brand? Would it still work? Would it cause any harm?
Circlotron:

--- Quote from: Nominal Animal on March 16, 2021, 02:39:30 pm ---For example, if we use antibacterial detergents everywhere, and antibiotics for every bacterial and/or viral infection, then we actually provide evolutionary pressure for bacteria and viruses to evolve protection against them.  Superbugs (antibiotic-resistant bacteria) didn't just appear out of nowhere; we forced bacteria to evolve that way.

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I've heard some say that the above situation, rather than cause a new entity to evolve, instead wipes out all the weak versions and leaves the previously minority but very strong and therefore unaffected versions with the entire environment all to themselves so now they can multiply unchecked. Disclaimer - I have no particular understanding of these things.
JohnnyMalaria:

--- Quote from: Circlotron on March 17, 2021, 11:40:43 pm ---I wonder what would happen if you got the first dose of one brand of vaccine and the second does of a different brand? Would it still work? Would it cause any harm?

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It would be less likely to work because the optimum time between first and second doses is different. The clinical trials determined the optimum time as defined by the maximum reduction in hospitalizations. (Sorry, that's a fugly word but I've lived in the US long enough...) If you get the second dose too early or too late, then its likely efficacy will be reduced.

As for harm? That hasn't been tested. Some of the vaccines are mRNA-based, some aren't. In the former case, it would depend on which proteins found in the coronavirus your body has been fooled into synthesizing in order to stimulate an immune response. And, harm, in such case, would be insufficient protection rather than direct damage to your health.

I'd be much more concerned about how your particular healthcare system would screw that up, though.
langwadt:

--- Quote from: Circlotron on March 17, 2021, 11:45:59 pm ---
--- Quote from: Nominal Animal on March 16, 2021, 02:39:30 pm ---For example, if we use antibacterial detergents everywhere, and antibiotics for every bacterial and/or viral infection, then we actually provide evolutionary pressure for bacteria and viruses to evolve protection against them.  Superbugs (antibiotic-resistant bacteria) didn't just appear out of nowhere; we forced bacteria to evolve that way.

--- End quote ---
I've heard some say that the above situation, rather than cause a new entity to evolve, instead wipes out all the weak versions and leaves the previously minority but very strong and therefore unaffected versions with the entire environment all to themselves so now they can multiply unchecked. Disclaimer - I have no particular understanding of these things.

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isn't that basically the evolve in evolution?


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