In my younger years, I was projecting and building hi-fi and guitar tubes amplifiers.
For guitar amplifiers, musicians were seeking for amplifiers with high distortion for "coloring" the sound of their musical instrument.
I then chosed universal low quality output transformers and I biased tubes (mostly EL34) for low quiescent current (working nearby class B)
For Hi-Fi stereo, I chosed expensive and high end output transformers as the most important components in a tube amplifier are the output transformers. (with push pull EL84 / 9W or EL34 / 25W)
What whe were looking for is just what we obtained later with the transistorized amplifier performance.
But there is a big difference between a tube amplifier and a transistor amplifier : the damping factor. (low for a tube amplifier, high for a transistor amplifier)
On this point, the best is the enemy of the good.
With a tube amplifier, loudspeakers operate more freely in their natural resonant frequency, which gives a more pleasing sound to the ear.
I think that's why music lovers say the sound of a tube amp is more enjoyable than a transistor amplifier. (with the same speakers)
NB: I also fully agree with dannyf about speakers and room acoustics...