Important is what printer it is, and how was the previous info put on the paper. If the old was laser printed you will probably have some slight issues with fuser spotting as it remelts the toner, especially if it is an older fuser with high page count. However the drum wear will be the same as if you were doing full page prints, so simply use a cartridge if it is low during the job. If it was printed using a offset printer then you might have some slight paper path extra debris from the ink particles, but in both cases you will just have to refer to the manual and manually clean out the paper path fully before and after, and it will be fine. If it has a separate toner assembly and toner tank then no worries, drums used there are hard wearing and will survive. Refill cartridges with a new toner drum as well are hard surfaced, they last a lot longer in use.
I generally, with a HP M101dn, get 4000 pages plus out of a refilled cartridge, as opposed to the "Genuine HP" which does 1500 pages before empty, though with the refilled one for the last 2k pages the printer is kind of gently complaining that toner is "very low, approximately -- pages remaining" on every print job. Probably will get 5k pages before it runs out totally or starts getting streaks of light.