Of course, if you are familiar with DIY Audio, you can always find a lot of tube applications.
(However, I do have a general reserve about how the tube enthusiasts go around preaching their stuff; for me it's more a question of style than function. As an example, a very well known headphone amplifier uses tubes as a preamplifier stage while the actual headphone driving work is still performed by an OPAMP)
There is a somewhat resurgence of tube-powered audio devices for mass-consumer applications. I've recently found in my local multimedia/records/electronic superstore an iPod station with two small pre-amplifier tubes and a magic eye tube.
If you want to play with tubes, please go ahead. This a perfectly good aspect of the electronics hobby. But don't have unreasonable expectations about it. Specifically, don't try to build from the start your next mega watt audio amplifier, everything will be too costly (especially the output transformer). I enjoy toying with old technology (Nixie tubes FTW) but I've spent too much time in my youth around smelly old TVs and radio stations to like tubes.