So funny ... a "sour" geek critiquing a nerd comedy show.
Though aimed at at the wider audience it naturally appeals to the nerd inside and out.
If you don't enjoy it, fine ... for you.
Don't waste your time trying to justify your dislike to the rest of us.
Two of your gripes have already been shown to be fallacious, the audience and the science validity, best quit while you're ahead.
TBBT FTW