General > General Technical Chat
Working From Home - Impacts of Coronavirus
cdev:
A stilbenoid polyphenol, resveratrol, which is found in a great many plants, looks to me like it might be helpful. (But it might not be, too)
People have used RESV to inhibit numerous other viruses and it does show in vitro activity against MERS and SARS.
Also, a number of medical informatics programs scanning for promising lead molecules point it out because it seems to have affinity to the spike protein of COVID-19.
It may be a good representative of a whole new way to approach viruses.
But we don't know. (It could do nothing, or even make it worse) It needs the research community's attention.
It did help with MERS. (related virus)
It can be aerosolized. It helps with acute lung injury caused by a standard inflammatory substance (LPS which is found in the large intestine, its a toxin made by bacteria) .
It would be helpful if any of you are doctors, or knew doctors, if you could get them to read those links. Smart doctors will read them, not take a position first. (unless they actually know the answer, which it appears to me that nobody does)
It just seems to me like we may be ignoring a substance with great potential to help people.
thinkfat:
--- Quote from: cdev on May 12, 2020, 02:56:34 pm ---It just seems to me like we may be ignoring a substance with great potential to help people.
--- End quote ---
It is of no consequence on the grand scale if the few us here ignore it. I do wonder, very much so, what drives your insistence in this being the right forum for shilling grape seed and red wine.
cdev:
You're misunderstanding me completely. I'm sorry. As I sit here I am listening to a Senate committee hearing which is talking about the US's response to COVID-19. I know a lot about functional foods, and have since I was young. I'm trying to help.
All ideas with any merit at all should be evaluated. Especially inexpensive, easy to implement ones.
The science is solid.
I don't know what else to say. It might help. And then again it might not.
I have no financial stake in anything. Shilling implies selling. I have nothing I'm selling.
--- Quote from: thinkfat on May 12, 2020, 03:40:10 pm ---
--- Quote from: cdev on May 12, 2020, 02:56:34 pm ---It just seems to me like we may be ignoring a substance with great potential to help people.
--- End quote ---
It is of no consequence on the grand scale if the few us here ignore it. I do wonder, very much so, what drives your insistence in this being the right forum for shilling grape seed and red wine.
--- End quote ---
Grapes and wine, as far as I know, even if it did help, I suspect its likely grapes and wine would not contain enough resveratrol to be that useful. Since we all want to see people be able to return to normalcy we need to respond to this illness. Actually, we do know that RESV is helpful with some kinds of influenza. Low dose RESV may help build immunity when combined with vaccines.
Look on PubMed and you'll see its a very unique substance immunologically.
What we MAY be able to do is something like this.
Antiviral Effect of Resveratrol in Piglets Infected with Virulent Pseudorabies Virus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164078/
I have no idea if it would work. I am just saying that they should investigate it in the COVID-19 context. This investigation is urgently needed.
because there is a real chance that it might work and because it would be so easy to implement if it does work.
Buriedcode:
cdev, this is like the fifth thread where you've mentioned resveratrol. Several relating to COVID-19 but also anything relating to health.
I understand you believe in it as a cure-all, but, if some compound/chemical/"extract" or supplement appears to help with a wide range of problems, then its probably bollocks. I don't understand your obsession with it. If you search the forum for "resveratrol" you'll find quite a few results, all by you (surprisingly, my post replying to yours in an earlier thread isn't there).
You link to a study on resveratrol vs a pseudorabies virus - what makes you think that virus is anything like this latest coronavirus?
Simply stating "it might be helpful, it might not" isn't really saying anything. Eating two cucumbers a day might help with, I dunno, arthiritis.. then again, it might not.
As I said in a previous thread, there is little evidence for any benefit to supplementation. No-one, as far as I can see, is suggesting its completely ineffective for anything, just that, I have yet to find any credible evidence for a benefit.
I'm sure there are thousands investigating the many drugs that have already been proven to be safe, and just look at what happens when people ignore the evidence and go with what they believe in? https://sciencebasedmedicine.org/covid-19-out-of-control-science-and-bypassing-science-based-medicine/
Time and resources (and in some cases lives) were wasted because people liked the idea that there was this random drug that magically cured people, rather than follow the evidence.
james_s:
--- Quote from: GlennSprigg on May 12, 2020, 11:51:17 am ---Regarding your last sentence, (mainly)...
Why would it be 'difficult' constitutionally?? Can't your President 'Mandate' what is to be done, like our Prime minister? I would have assumed that there are special 'bylaws' that cover certain times like 'Wars' (and this present scenario!) that Military Law etc can be in effect!??
As to 'Boundaries', yes, in the USA it has spread all over, but please consider this!!...
Our State of Western-Australia is quite large, so apart from Interstate travel restrictions/blocks, our state is divided up (NOW!) into multiple areas, for boundary/isolation. Now, Perth, our main City, is virtually where ALL the cases are!! 200kms South of Perth, are multiple major townships/areas like Bunbury, Bussleton, Margaret-River etc etc are in our own isolated area here in W.A. where we can not travel to the likes of Perth, and visa versa. Now we have NO infections in our 'zone', so as long as no-one crosses into our 'zone', then NO-ONE here WILL !! This must eventually govern 'our' restrictions here?
--- End quote ---
The constitution includes a right to travel which prevents things like locking down state borders. The president has very little real authority, contrary to what the one we currently have in office likes to think. They cannot simply suspend the constitutional rights of citizens without doing something very extreme like declaring martial law. It's the sort of thing likely to incite an armed revolt in this country. It's not impossible, but it would be difficult and a political death sentence in the more conservative areas.
https://en.wikipedia.org/wiki/Freedom_of_movement_under_United_States_law
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