Two simple things: if you are actually not logged in to YT, many issues with adblockers disappear. Yes, this is odd, and I'm not sure I get the rationale. Of course in that case you can't comment and most settings won't get saved.
If you use Firefox, opening YT pages in a "private window" will also make almost all annoyances disappear.
For now.
That's consistent with the fact that clearing cookies also helps.