I used to etch my DIY boards, but after building a decent CNC a few years ago, I will never go back to etching.
Sure it's not all clean and the dust is not healthy at all, but I got mine enclosed in a box with an acrylic window.
For mounting, I use a scrap piece of wood on the bed that I plane once a month or so, then simply double sided tape to hold the board in place during milling and drilling.
Only takes like 20-30 minutes for a medium sized board from start until finish with holes and everything.
I don't remove all the copper, just enough to make sure there are no shorts and it's easy to solder.
Like this one:
Sure the cost of a decent setup would pay for a lot of manufactured boards, but the convenience of just doing a quick layout and having something you can start soldering within an hour is very nice.
I am however not convinced the advertised "Othermill" machine will work very well, also it seems very expensive for that size and materials.