Top side, fine pitch SMD/SIP footprint, 12th pin from bottom: there's a ground fill inbetween traces, with no via(s) in it, and with too fine a neck (I normally set polys to 10 mil clearance and 10 mil min neck size, but here it looks finer than your other traces besides).
I see very little ground filling above or below any of those routes/footprints, which is made very difficult by the presence of rows of pins on both top and bottom -- there's no room for ground to fill around either.
Ideally, you should have ground beneath anything on top, or above anything below, and stitched around. Any place you have traces and footprints occupying both sides, no ground can fill in, and signal quality suffers.
Just for pushing voltage around, it's probably fine, but beware if you have fast risetimes (which is typical for the outputs of most any MCU or SPI or other device), you can very easily get overshoot, ground bounce, crosstalk, clock glitches... A good treatment is to source terminate logic pins, by adding a resistor (33 ohms or more). Smaller values prevent ringing, larger values reduce the risetime.
Remember, only use as much bandwidth (or rise time) as you need. For the same reason, don't forget to filter (and usually ESD protect, as well) external connections, etc.
Tim