Nothings changed much, Altium is still a defacto standard in industry. KiCAD has gotten much better, but Eagle and KiCAD et.al likely aren't going to impress anyone much on a resume at any decent sized company.
If you have access to an Altium license then learn that.
If your job is full-time PCB layout, then sure, you want to have gobs of experience using the tools used by potential employers.
If your job is design engineer, then experience with any PCB CAD tool is fine, and honestly, if you're anything other than a freshout, you've had experience with at least one such tool, and you should be able to come up to speed on any other in a short amount of time. This is because you already know
what you are trying to accomplish, and it becomes a matter of learning the menus and working with your employer's libraries. You draw the schematic, add design rules (either in the schematic or in notes to the layout person) and hand it off to layout.