Cam350 is a basic tool where you can indeed do some panelisation work , but it ' nowhere near Genesis or Ucam. I know CAM350 also has problems with certain gebrer features ( complex polygons and some arcs ).
Ucam has NO problems with gerber. They own the standard

Ucam is the direct descendant from the Gerber corporation , sold to intergraph , then to Barco thento Mania and now incorporated as UcamCo.
Genesis is another 'old name'.
Go to any pcb fab and ask them what they run to do their fab processing. It's going to be either Ucam or Genesis (frontline) you can do things like pattern shrinking or expansion to compesate for etching , all kinds og logic operations on layers , converting flashes to strokes and reverse , converting polygons to strokes or meshes to polygons and much much more. Boolean operations between layers / entities.
Of course, the question is : do you need that ? A pcb fab does, but a pcb designer doesn't. If it can't be done in the pcb design tool , you probably won't need it as it is fab related. Leave the fab stuff to the fab. You don't have the expertise anyway.