From what I can tell, the only thing that really doesn't work on win7-64bit is macros. Unfortunately that is a deal breaker for me as I have my layer macros for layout all set up and I'd go crazy without them. I just run pcad in a winxp virtual machine when I have to use that computer. It's funny that I can't convince anyone to upgrade to altium designer because they are scared off by the FPGA stuff.