sometimes there are marks every 5 or 10 pads to for easier counting during testsing, sometimes higher voltage tracks are marked to indicate the high voltage and lower the chance for accidental / casual measurements.
In general silkscreen is not used for voltage isolation. It's likely to improve isolation (a bit), but it can not be guaranteed or relied upon. But there are also other options such as conformal coatings that are especially designed to improve insulation, moisture and dirt resistance, etc.